Non-profit or commercial entities

Image for Non-profit or commercial entities

Translational Science Benefits

Icon for Clinical & medical benefits


Icon for Community & public health benefits


Icon for Economic benefits


Icon for Policy & legislative benefits


Economic benefits (Commercial products)


Creation of businesses or non-profit organizations. Nonprofit organizations often focus on a specific disease, supporting preclinical and clinical development and increasingly, overseeing project management. Commercial entities support the production, distribution, and marketing of a wide variety of research products and services to bring them to the market. Examples include organizations that could connect basic scientists and clinicians in specific areas to move studies forward, aid in the dissemination of new diagnostic procedures, or help increase access to services in low-resourced communities.


Creating a commercial or nonprofit organization helps increase the translational impact of scientific discoveries by helping to reach more people. Organizations that are established as a result of an existing need in translational research or a need identified through clinical and translational research can have benefits all along the translational research continuum.


Advice from authors on searching for information:

The background information on how a business or non-profit entity was founded either directly or indirectly as a result of advances in clinical or translational science may be difficult to locate in general, and more or less straightforward to find in specific instances. Those researchers and administrators interested in a particular organization should first try to contact founders or original researchers from the source project. Others interested in more general examples of organizations arising out of translational research may try to narrow searches to specific sectors (e.g., non-profit organizations in genomic services or businesses offering health care transportation services).

Resources & Data

Organizations, repositories, websites, and other sources where you can find more information:



Data Limitations

Challenges you may encounter while searching for information:

While there are many lists of both non-profit organizations and businesses at many geographic levels (e.g., local, state, national, regional, and global), most are incredibly lengthy and may or may not contain information on the rationale for the founding of each entity.


Articles, books, and other publications in translational science using the indicator:

Case Studies

Oxysterols for Treatment of Perinatal Brain Injury

By Duke University Clinical & Translational Science

A first-in-class therapy to prevent cerebral palsy in premature infants.

Using 3D Holograms to Treat Cardiac Arrhythmia


Developing and using 3D hologram technology (ELVIS) to guide physicians during cardiac ablation procedures.

Advancing the Science of Addiction Recovery


Improving addiction outcomes through the CAPA Collaboration (a community-university partnership) and the development of a clinical dashboard to guide and track recovery.