Guidelines

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Translational Science Benefits

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Clinical

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Economic

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Policy

Clinical & medical benefits (Procedures & guidelines)

Definition

Formal recommendations or principles to assist with patient care for specific clinical circumstances. Guidelines are issued by professional organizations, government agencies, and nonprofit organizations (e.g., American Academy of Pediatrics, American Medical Association, World Health Organization, U.S. Preventive Services Task Force).

Rationale

Guidelines promote quality and effectiveness of health care services and procedures. Development of guidelines is based on extensive and systematic review of the literature to provide the evidence to support recommendations. Guidelines can serve as helpful evidence of translational research efforts that translate into improved health care services and procedures.

Guidance

Advice from authors on searching for information:

Groups such as government agencies (federal, state, and local), institutions, professional societies, governing boards, vendors, or expert panels issue guidelines. Guidelines are also produced by vendors not affiliated with a governmental agency or specialty organization. One example of this type of guideline is the Evidence-Based Care Sheets produced by Current Index to Nursing and Allied Health Information (CINAHL). The Sheets include a list of references used to support the guidelines.

Review of guidelines is required to locate evidence that findings from research were used to support the implementation of a guideline. Most guidelines contain references to the literature to support the recommendations noted in the guideline.

Start with the Data Sources to find guidelines for a specific disease, disorder, or condition. Search using the keywords related to the topic, the title of the research study, and/or name of the researcher. Also, check the websites of sponsoring groups or professional societies that convene to develop guidelines.

Resources & Data

Organizations, repositories, websites, and other sources where you can find more information:

  • Agency for Healthcare Research and Quality (AHRQ). The Agency for Healthcare Research and Quality (AHRQ) is the lead Federal agency charged with improving the safety and quality of America’s health care system. AHRQ develops the knowledge, tools, and data needed to improve the health care system and help Americans, health care professionals, and policymakers make informed health decisions. In doing so, AHRQ sponsors the development of guidelines, reports, toolkits, and other materials.
  • ECRI Guidelines Trust. ECRI Guidelines Trust now provides summaries of evidence-based clinical practice guidelines. A free account is required to search Guidelines Trust. See FAQs and Search Tips for more information.
  • National Guideline Clearinghouse (NGC). The National Guideline Clearinghouse is a public resource for summaries of evidence-based clinical practice guidelines. See NGC Help & About for guidance. This resource was removed as of July 16, 2018, due to a lack of federal funding.
  • PubMed/MEDLINE. PubMed provides free access to MEDLINE, the NLM database of indexed citations and abstracts to medical, nursing, dental, veterinary, health care, and preclinical sciences journal articles. See PubMed Help for guidance.

Data Limitations

Challenges you may encounter while searching for information:

There is no single resource for clinical guidelines. Access to self-reported researcher or administrative/in-house data may be required to locate documentation.

Publications

Articles, books, and other publications in translational science using the benefit:

Case Studies

Identifying and Addressing Traumatic Stress and Suicidality in Youth Served by Children’s Advocacy Centers

By Implementation Research Institute (IRI)

Assessing the effectiveness of a trauma screening and response protocol to expand access to mental health care for youth in rural Children’s Advocacy Centers.

Clinical & medical benefits

Community & public health benefits

Economic benefits

Policy & legislative benefits

Increasing Access to Buprenorphine in Rural Primary Care 

By Implementation Research Institute (IRI)

Assessing the effectiveness of a buprenorphine prescribing support program to expand access to opioid use disorder treatment in rural primary care settings.

Clinical & medical benefits

Community & public health benefits

Economic benefits

Policy & legislative benefits

A young boy sits in a chair as he receives his chemotherapy treatment intravenously.

Transforming Tears to Smiles: Reducing Needle-based Procedural Pain in Children with Cancer Globally

By St. Jude Global

The Global Comfort Promise initiative reduces needle pain and anxiety for children with cancer in low- and middle-income countries, supporting better adherence to treatment plans and ultimately improving health and survival outcomes

Clinical & medical benefits

Community & public health benefits

Economic benefits

Policy & legislative benefits